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Updated: Jun 11, 2026

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
10:33

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

サイクリン依存キナーゼ阻害剤であるダカポは,ドロソフィラの発達中に細胞増殖を止めます

M E Lane1, K Sauer, K Wallace

  • 1Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft, Tübingen,Federal Republic of Germany.

Cell
|December 27, 1996
PubMed
まとめ

ダカポ遺伝子は,ドロソフィラの細胞サイクル停止を調節し,分化前に余分な分裂を防ぐ. この阻害剤は,サイクリンE/cdk2の活性を制御することによって,適切な発達のタイミングを保証します.

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