異例なRelのような構造が,転写因子NFATccのDNA結合領域にある

S A Wolfe1, P Zhou, V Dötsch

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Nature
|January 9, 1997
PubMed
まとめ

研究者らは,免疫応答の調節に不可欠なNFATc DNA結合ドメイン (NFATc-DBD) を特定した. この発見は,NFATを直接標的とする新薬の開発に役立ち,免疫抑制療法による副作用を潜在的に軽減します.

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