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ストレスシグナルキナーゼSek1は,チモサイトをCD95およびCD3によって媒介されるアポトーシスから保護します

H Nishina1, K D Fischer, L Radvanyi

  • 1The Amgen Institute, Ontario Cancer Institute, Toronto, Canada.

Nature
|January 23, 1997
PubMed
まとめ

Sek1 (JNKK/MKK4) はT細胞の発達に不可欠である. Sek1がアポトーシスから保護されたチモサイトを削除し,T細胞成熟時の生存信号を媒介する役割を示しています.

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