妊娠中絶後の6ヶ月間における重度のうつ病障害
R Neugebauer1, J Kline, P Shrout
1Epidemiology of Developmental Brain Disorders Department, New York State Psychiatric Institute, New York, NY 10032, USA.
JAMA
|February 5, 1997
まとめ
流産した女性は,6ヶ月以内にメジャーうつ病 (MDD) のリスクが高くなりますが,特に子供を持たない場合です. 早期のモニタリングとサポートは,妊娠中絶後のこれらの女性にとって非常に重要です.
科学分野:
- 生殖器保健は,生殖器の健康についてです.
- メンタルヘルス メンタルヘルス
- 精神科医は精神病を患っている.
背景:
- 流産を含む妊娠中絶は,女性の精神的健康に影響を与える重要な出来事です.
- 以前の研究では,不良生殖イベントとそれに続く気分障害との関連が示唆されているが,特定のリスク要因については,さらなる解明が必要である.
研究 の 目的:
- 流産後の6ヶ月間にメジャーうつ病 (MDD) を発症するリスクを調査する.
- 妊娠中絶を経験した女性の特定のサブグループを特定し,MDDのリスクが高く,子供を持たない女性,生殖能力の喪失を経験した女性,高齢女性を含む.
- 妊娠中絶時の妊娠年齢や妊娠に対する女性の態度によってMDDのリスクが変化するかどうかを調べる.
主な方法:
- コホート研究デザインを用いて,流産を経験した女性 (n=229) とコミュニティベースの対照群 (n=230) を比較した.
- 重度のうつ病は,診断面接スケジュールを用いて評価されました.
- 参加者は,自発的中絶のための医療センターに通っている女性と,マッチしたコミュニティのサンプルでした.
主要な成果:
- 流産した女性は,対照群 (4.3%) に比べて,MDDを発症するリスクが著しく高かった (10.9%),全体の相対リスク (RR) が2.5.5であった.
- 子供を産む女性 (RR=1.3) と比べて,子を持たない女性ではリスクがかなり高かった (RR=5.0).
- 流産グループにおけるMDD症例の大部分は,流産後の最初の1ヶ月以内に始まり,MDD歴のある患者の54%が再発を経験しました. リスクは,前回の生殖能力の喪失,母親の年齢,妊娠期間,または妊娠に対する態度によって有意に変化しませんでした.
結論:
- 流産を経験した女性は,特に流産後の最初の数週間で,重度のうつ病のリスクが高まります.
- 子を持たない女性,および重度のうつ病歴のある女性は,厳密な監視を必要とする高リスクグループとして特定されています.
- 医療提供者は,妊娠中絶の女性,特に高リスクカテゴリーに属する女性に対して,サポートカウンセリングまたは精神薬理学的治療を検討すべきである.
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