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Updated: Jul 20, 2026

Methods for Evaluating the Role of c-Fos and Dusp1 in Oncogene Dependence
10:09

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Published on: January 7, 2019

c-Myc誘発のアポトーシスの抑制は,PI(3) KとPKBを通じたRas信号によるシグナル伝達によって行われます

A Kauffmann-Zeh1, P Rodriguez-Viciana, E Ulrich

  • 1Imperial Cancer Research Fund, London, UK.

Nature
|February 6, 1997
PubMed
まとめ

Rasシグナリングは矛盾する経路を活性化し,フォスファディチルノシトール-3キナーゼ (PI(3) K) とタンパク質キナーゼB/Akt経由でc-Myc誘発のアポトーシスを抑制するが,Raf経路経由でアポトーシスを促進する.

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