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Updated: Jun 20, 2026

Single Cell Measurements of Vacuolar Rupture Caused by Intracellular Pathogens
10:39

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細胞壁バイオシンセシスと分解制御のためのサイトソリック中間物質は,グラム陰性細菌における誘導可能なベータラクタム抵抗性を誘導します

C Jacobs1, J M Frère, S Normark

  • 1Centre d'Ingénierie des Protéines, Université de Liège, Belgium.

Cell
|March 21, 1997
PubMed
まとめ

グラム陰性細菌は,AmpRとムロペプチドを使用してβ-ラクタマース生成を制御する. ムロペプチドは,UDP-MurNAc-pentapeptideを阻害し,アンムルNAc-トリペプチドは,β-ラクタマース合成のAmpR活性化を回復することで,敵対的に作用する.

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