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Updated: Aug 19, 2026

A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates
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セックス・レタルは,ドロソフィラの非スプライシングメカニズムによるドーゼ補給を制御する

R L Kelley1, J Wang, L Bell

  • 1Department of Cell Biology, Baylor College of Medicine, Houston, Texas 77030, USA.

Nature
|May 8, 1997
PubMed
まとめ

セックスレタル (SXL) タンパク質は,雌ドロソフィラの男性特異的なレタル2 (msl2) 遺伝子発現を抑制する. SXLはmsl2RNAと結合し,投与量の補償のためにスプライシングを変化させるのではなく,翻訳を抑制する.

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