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Updated: Sep 17, 2026

Cell Aggregation Assays to Evaluate the Binding of the Drosophila Notch with Trans-Ligands and its Inhibition by Cis-Ligands
05:48

Cell Aggregation Assays to Evaluate the Binding of the Drosophila Notch with Trans-Ligands and its Inhibition by Cis-Ligands

Published on: January 2, 2018

プレセニリン1は,パラキシアルメソダーマのNotch1およびDII1発現に必須である

P C Wong1, H Zheng, H Chen

  • 1Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA. pcwong@welchlink.welch.jhu.edu

Nature
|May 15, 1997
PubMed
まとめ

プレセニリン1 (PS1) は,胚の発達に不可欠であり,骨格のパターニングに不可欠なNotchシグナリングを調節します. PS1欠乏症は,Notch1とDll1の発現を低下させることで,ソミットセグメンテーションを乱します.

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Real-time Bioluminescence Imaging of Notch Signaling Dynamics during Murine Neurogenesis

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