関連する実験動画

Updated: Jun 29, 2026

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
10:44

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing

Published on: May 5, 2023

スプライシング因子BBPは,プレ-mRNA分岐点配列UACUAACACと特異的に相互作用する

J A Berglund1, K Chua, N Abovich

  • 1Howard Hughes Medical Institute, Department of Biology and Biochemistry, Brandeis University, Waltham, Massachusetts 02254, USA.

Cell
|May 30, 1997
PubMed
まとめ

ブランチポイントブリッジングタンパク質 (BBP) は,酵母前mRNAのUACUAAC配列に結合する. 哺乳類のオートログであるSF1もこの配列を結合し,BBPが両方の生物における分岐点の定義における役割を示唆している.

さらに関連する動画

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions06:50

Computational Prediction of Amino Acid Preferences of Potentially Multispecific Peptide-Binding Domains Involved in Protein-Protein Interactions

Published on: January 26, 2024

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System07:59

Rapid and Specific Detection of Acinetobacter baumannii Infections Using a Recombinase Polymerase Amplification/Cas12a-based System

Published on: April 25, 2025

関連する概念動画

GPCRs Regulate Adenylyl Cylase Activity01:09

GPCRs Regulate Adenylyl Cylase Activity

Some GPCRs transmit signals through adenylyl cyclase (AC), a transmembrane enzyme. AC helps synthesize second messenger cyclic adenosine monophosphate (cAMP). AC catalyzes cyclization reaction and converts ATP to cAMP by releasing a pyrophosphate. The pyrophosphate is further hydrolyzed to phosphate by the enzyme pyrophosphatase, which drives cAMP synthesis to completion. However, cAMP is rapidly degraded to 5′ AMP by the enzymes phosphodiesterase (PDE), preventing overstimulation of cells.
Two...
AC Sources01:20

AC Sources

Direct current is a flow of electric charge in only one direction and has a steady state of constant voltage in the circuit. Rectifiers, batteries, commutator-equipped generators, and fuel cells are some examples of devices that generate direct current. Nowadays, most applications use a time-varying voltage source. Alternating current is a flow of electric charge that periodically reverses direction. An alternating current is produced by an alternating emf that is generated in a power plant. If...