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Updated: Aug 9, 2026

Unraveling Entropic Rate Acceleration Induced by Solvent Dynamics in Membrane Enzymes
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Published on: January 16, 2016

酵素の触媒力における軌道方向調整:小さな構造的変化が大きな触媒的影響を及ぼす

A D Mesecar1, B L Stoddard, D E Koshland

  • 1Department of Molecular and Cell Biology, Stanley Hall, University of California, Berkeley, CA 94720, USA.

Science (New York, N.Y.)
|July 11, 1997
PubMed
まとめ

イソチラート脱水素酶 (IDH) のように,酵素構造の変更は,精密な基板の配列が酵素触媒の鍵であることを明らかにします. 正確な指向から最適な軌道重複は,酵素の力を大幅に高めます.

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