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Updated: May 12, 2026

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Daxxは,JNKとアポトーシスを活性化する新しいFas結合タンパク質です

X Yang1, R Khosravi-Far, H Y Chang

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA.

Cell
|June 27, 1997
PubMed
まとめ

研究者らは,Fas媒介によるアポトーシスを強化し,Jun N-端末キナーゼ (JNK) 経路を活性化するタンパク質であるDaxxを発見しました. ダックス (Daxx) は,ファス (Fas) の下流で,FADD経路と並行して,明確なアポプトシス経路を定義しています.

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