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Updated: May 14, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
11:37

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry

Published on: November 29, 2013

Hsp90分子チャペロンのATP/ADP結合部位の識別と構造的特徴付け

C Prodromou1, S M Roe, R O'Brien

  • 1Department of Biochemistry and Molecular Biology, University College London, United Kingdom.

Cell
|July 11, 1997
PubMed
まとめ

この研究は,Hsp90チャペロンがATPと直接結合し,長年にわたる論争を解決することを明らかにしています. 結晶構造は,ゲルダナミシンがこの核酸結合部位をブロックし,その作用メカニズムを明らかにすることを示しています.

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