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Updated: Jul 10, 2026

Using Confocal Analysis of Xenopus laevis to Investigate Modulators of Wnt and Shh Morphogen Gradients
08:10

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Published on: December 14, 2015

コスタル2 (Costal2) は,ヘッジホッグのシグナル伝達経路における新しいキネシン関連タンパク質です

J C Sisson1, K S Ho, K Suyama

  • 1Department of Developmental Biology, Howard Hughes Medical Institute, Stanford University School of Medicine, California 94305-5427, USA.

Cell
|July 25, 1997
PubMed
まとめ

キネシンに関連するタンパク質であるCostal2は,シグナル応答性細胞であるヘッジホッグ (HH) に蓄積される. このタンパク質は,Cubitus interruptus (CI) 転写因子と結合し,Costal2がHH経路の活性を直接調節することを示唆しています.

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Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis07:26

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