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Updated: May 3, 2026

Retroviral Transduction of T-cell Receptors in Mouse T-cells
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I型糖尿病における自己免疫遺伝子候補としてヒト内生レトロウイルス超抗原

B Conrad1, R N Weissmahr, J Böni

  • 1Department of Genetics and Microbiology, University of Geneva Medical School, Switzerland.

Cell
|July 25, 1997
PubMed
まとめ

新型レトロウイルスにコードされた超抗原 (SAG) は,インスリン産生ベータ細胞を破壊するT細胞を活性化することで1型糖尿病を引き起こす可能性があります. この発見により,1型糖尿病の病原化に寄与する潜在的自己免疫遺伝子が特定されました.

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