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Updated: Aug 24, 2026

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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転写因子NF-kappaBBを活性化するサイトカイン反応性イカッパBキナーゼ

J A DiDonato1, M Hayakawa, D M Rothwarf

  • 1Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California at San Diego, La Jolla 92093-0636, USA.

Nature
|August 7, 1997
PubMed
まとめ

イカッパBキナーゼ (IKK) 複合体はイカッパBタンパク質をリン酸化し,NF-kappaBの活性化につながります. この浄化されたセリンキナーゼは,NF-kappaBシグナル伝達経路の調節に不可欠です.

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