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Updated: Aug 9, 2026

Tandem Affinity Purification of Protein Complexes from Eukaryotic Cells
11:30

Tandem Affinity Purification of Protein Complexes from Eukaryotic Cells

Published on: January 26, 2017

マルチメリックMHCクラスI-TAP複合体の組立と機能におけるタパシンの重要な役割

B Ortmann1, J Copeman, P J Lehner

  • 1Howard Hughes Medical Institute, Section of Immunobiology, Yale University School of Medicine, 310 Cedar Street, New Haven, CT 06510, USA.

Science (New York, N.Y.)
|August 29, 1997
PubMed
まとめ

タパシンは,メジャー・ヒストコンパティビリティ・コンプレックス (MHC) のクラスI分子と抗原処理 (TAP) に関連するトランスポーターとの相互作用を促進する重要なタンパク質です. その発現は,欠乏した細胞における正常な抗原表現と免疫細胞認識を回復させます.

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