身体活動の急激な増加は,椎間板の変性を引き起こす可能性がありますか?
Lancet (London, England)
|September 18, 1997
まとめ
高度の身体活動により,椎間板が他の組織のように迅速に適応できないため,腰椎椎間板変性を引き起こす可能性があります. これにより,彼らは重荷を負った脊椎の弱いリンクになります.
科学分野:
- バイオメディカルエンジニアリング
- 整形外科 整形外科 整形外科
- 脊椎生体力学 脊椎生体力学
背景:
- 流行病学的な研究は,背中の下部の重複的な負荷と椎間板の変性との相関関係を示しています.
- 体脊椎の実験では,重複的な機械的負荷が,退化に一致する腰椎椎間板の障害を引き起こす可能性があることが示されています.
研究 の 目的:
- 脊椎間盤が,他の筋骨格組織と異なり,重複的な機械的負荷に反応して強くならない理由を調査する.
- 腰椎椎間板の低代謝率が彼らの適応的改造を阻害し,身体活動が増加したときに傷害を受けやすいという仮説を提案し,テストする.
主な方法:
- 身体活動とディスク変性との関係を示す疫学データのレビュー.
- 組織の適応と代謝率を制御する生体力学的原理の分析.
- 脊髄組織に関する実験室での調査 (詳細は要約に記載されていません).
主要な成果:
- この仮説は,腰椎椎間板の低代謝率が,無血管性であるため,増加した機械的負荷に適応することを妨げると仮定しています.
- この代謝の制限により,腰椎椎間板は,体力の増加により適応的な強化を受けている脊椎の"弱いリンク"になることがあります.
- 予備的な実験室での発見は,この仮説を裏付けている.
結論:
- 身体活動の増加は,メタボリック適応と再構築のためのディスクの限られた能力のために,腰椎椎間板変性につながる可能性があります.
- この仮説を検証するために,最近のディスク変性と最近の身体活動の増加を直接関連付けるために,さらなる臨床的証拠が必要である.
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