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Updated: Jun 24, 2026

Assaying Protein Kinase Activity with Radiolabeled ATP
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二重リン酸化によるMAPキナーゼERK2の活性化メカニズム

B J Canagarajah1, A Khokhlatchev, M H Cobb

  • 1Department of Biochemistry, The University of Texas Southwestern Medical Center at Dallas, 75235-9050, USA.

Cell
|September 23, 1997
PubMed
まとめ

ミトゲン活性化タンパク質 (MAP) キナーゼERK2の活性形態は,リン酸化が酵素を活性化する方法を示しています. アクティベーションリップと特異性ポケットの重要な構造の変化は,ERK2を説明します.

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