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Updated: Jul 21, 2026

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シングルサイクルヌクレオチドゲートチャネルは,異なるリガンド結合状態でロックされています

M L Ruiz1, J W Karpen

  • 1Department of Physiology, University of Colorado School of Medicine, Denver 80262, USA.

Nature
|October 6, 1997
PubMed
まとめ

サイクルヌクレオチドゲート (CNG) チャンネルは,フォトアフィニティcGMPアナログを使用して,リガンド結合状態にロックされました. これにより,結合リガンドの数と相関する明確なチャネル開口が明らかになり,CNGチャネル活性化メカニズムが明確になりました.

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