妊娠中の妊娠中の妊娠糖尿病の決定因子の将来的な研究
C G Solomon1, W C Willett, V J Carey
1Section for Clinical Epidemiology, Division of General Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, Mass, USA.
JAMA
|October 7, 1997
まとめ
妊娠中糖尿病 (GDM) のリスクは,母親の年齢,糖尿病の家族歴,より高いBMI,体重増加,喫煙によって増加します. これらの要因を特定することは,妊娠前にGDMの予防に役立ちます.
科学分野:
- 産婦人科と産婦人科を担当しています.
- エンドクリノロジー エンドクリノロジー
- エピデミオロジー エピデミオロジー
背景:
- 妊娠中糖尿病 (GDM) は,妊娠の3〜5%に影響します.
- GDMの危険因子を特定することは,予防戦略を策定する上で極めて重要です.
研究 の 目的:
- 非インスリン依存性糖尿病のリスク要因がGDMのマーカーであるかどうかを判断する.
- ライフスタイルと人口統計的要因とGDMリスクとの関連性を評価する.
主な方法:
- 看護師の健康研究IIの女性14,613人を対象とした前向きなコホート研究.
- 医療記録のレビューによって検証された自己報告されたGDM診断.
- 年齢,BMI,その他のリスク要因をコントロールする多変量分析.
主要な成果:
- GDMのリスクは,母親の年齢,糖尿病の家族歴,妊娠前のBMIの高さ (25-29.9 kg/m2および≥30 kg/m2) に伴い,有意に増加しました.
- また,早期成人期におけるより大きな体重増加,非白人の民族,および現在の喫煙でリスクの増加が観察されました.
- 激しい運動は,GDMリスクの非有意な減少を示しました.
結論:
- 先進的な母性年齢,糖尿病の家族歴,非白人民族,より高いBMI,成人期の早期の体重増加,喫煙は,GDMリスクの増加を予測する要因です.
- これらの発見は,高リスク妊娠を特定し,妊娠前のリスク軽減戦略を伝えるのに役立ちます.
- 大幅な体重増加や喫煙を避けるなど,ライフスタイルの変更により,GDMの発生率が低下する可能性があります.
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