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レプチンは,ATPに敏感なカリウムチャネルの活性化により,下垂体ニューロンを抑制する

D Spanswick1, M A Smith, V E Groppi

  • 1Department of Biomedical Sciences, University of Aberdeen, Institute of Medical Sciences, Foresterhill, UK.

Nature
|December 11, 1997
PubMed
まとめ

体重調節のための重要なホルモンであるレプチンは,痩せたネズミの視床下部のカリウムチャネルを活性化します. 食欲のコントロールに不可欠なこのメカニズムは,肥満のラットでは障害があり,糖尿病との関連が示唆されています.

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