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Updated: Aug 11, 2026

Assaying Protein Kinase Activity with Radiolabeled ATP
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PDK1によるp70s6kのリン酸化と活性化

N Pullen1, P B Dennis, M Andjelkovic

  • 1Friedrich Miescher Institute, Maulbeerstrasse 66, CH-4058, Basel, Switzerland.

Science (New York, N.Y.)
|February 21, 1998
PubMed
まとめ

ミトゲンは,重要なタンパク質キナーゼであるp70s6kを活性化させ,そのリン酸化を促進します. フォスフォノシチド依存キナーゼ1 (PDK1) は,p70s6kを直接リン酸化して活性化し,タンパク質合成に影響を与えます.

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