HIV-1 ネフタンパク質は,細胞毒性Tリンパ球による殺戮から感染した原始細胞を保護する

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Updated: Aug 10, 2026

Preparation and Use of HIV-1 Infected Primary CD4+ T-Cells as Target Cells in Natural Killer Cell Cytotoxic Assays
12:07

Preparation and Use of HIV-1 Infected Primary CD4+ T-Cells as Target Cells in Natural Killer Cell Cytotoxic Assays

Published on: March 14, 2011

K L Collins1, B K Chen, S A Kalams

  • 1Department of Biology, Massachusetts Institute of Technology, Cambridge 02139, USA.

Nature
|February 5, 1998
PubMed
まとめ

ヒト免疫不全ウイルス (HIV-1) Nefタンパク質は,ウイルスクリアランスを阻害し,メジャー・ヒストコンパティビリティ・コンプレックス (MHC) クラスI発現を減少させることで,感染した細胞が細胞毒性Tリンパ球 (CTLs) を回避するのを助けます.

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Peptide-based Identification of Functional Motifs and their Binding Partners

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A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses14:23

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

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