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Updated: May 12, 2026

Examination of Thymic Positive and Negative Selection by Flow Cytometry
14:29

Examination of Thymic Positive and Negative Selection by Flow Cytometry

Published on: October 8, 2012

Bリンパ球の免疫耐性の発達調節は,受容体選択からクローン選択を区分する

D Melamed1, R J Benschop, J C Cambier

  • 1Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA.

Cell
|February 11, 1998
PubMed
まとめ

B型リンパ球の発達には,アポトーシスや受容体編集のような免疫耐性メカニズムが含まれています. この研究では,受容体の編集がアポトーシスの感受性より先行し,B細胞成熟時の受容体選択からクローン選択を分離していることが明らかになりました.

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