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Updated: Aug 18, 2026

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension
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エンドセリン-1は,ラットの肺内皮細胞培養におけるエンドセリン変換酵素-1の発現を阻害する

S Naomi1, T Iwaoka, T Disashi

  • 1Third Department of Internal Medicine, Kumamoto University School of Medicine, Honjo, Japan.

Circulation
|February 14, 1998
PubMed
まとめ

エンドセリン-1 (ET-1) は,肺細胞におけるエンドセリン変換酵素-1 (ECE-1) の発現を減少させます. このフィードバックメカニズムには,ETB受容体が関与し,ET-1生物合成に影響を与えます.

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