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Updated: Aug 13, 2026

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells
13:58

Peptide:MHC Tetramer-based Enrichment of Epitope-specific T cells

Published on: October 22, 2012

自己ペプチド-MHC抗原のT細胞受容体認識における可塑性の構造的基礎

K C Garcia1, M Degano, L R Pease

  • 1Department of Molecular Biology and the Skaggs Institute of Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|March 21, 1998
PubMed
まとめ

T細胞受容体 (TCRs) は,多様な自己および外来抗原を認識するために構成的変化を経験することによって,二重の特異性を示します. この構造的可塑性により,TCRは病原体検出のためにペプチド-MHC複合体をスキャンすることができます.

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