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Updated: May 1, 2026

Engineering and Evolution of Synthetic Adeno-Associated Virus AAV Gene Therapy Vectors via DNA Family Shuffling
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ハムスターの細胞に統合されたウイルス遺伝子のユニークなパターンが,高度に腫瘍性ヒトアデノウイルス12によって変形しました

M R Green, G Chinnadurai, J K Mackey

    Cell
    |March 1, 1976
    PubMed
    まとめ

    人間のアデノウイルス12 (Ad 12) のDNA配列はハムスターの細胞に統合され,ウイルスのDNAの93-100%が存在します. この研究は,細胞DNAにおけるヒトアデノウイルス遺伝子の共性結合の直接的な証拠を初めて提供しています.

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