関連する実験動画

Updated: Jul 29, 2026

GABA-activated Single-channel and Tonic Currents in Rat Brain Slices
09:59

GABA-activated Single-channel and Tonic Currents in Rat Brain Slices

Published on: July 17, 2011

PIP2による内向整流器のカリウムチャネルの直接活性化と,Gbetagammaによる安定化

C L Huang1, S Feng, D W Hilgemann

  • 1Department of Medicine, University of Texas Southwestern Medical Center at Dallas, 75235, USA. chuan1@mednet.swmed.edu

Nature
|March 5, 1998
PubMed
まとめ

内向整流器K+チャネルは,フォスファディチリノシトール4,5-ビスホスファート (PIP2) を直接結合し,その活動に不可欠である. グアニンヌクレオチド結合タンパク質 (Gタンパク質) ベータ-ガンマサブユニットは,このPIP2-チャネル相互作用を安定させ,チャネル機能を強化します.

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