高齢者の5年死亡率の危険因子:心臓血管健康研究
L P Fried1, R A Kronmal, A B Newman
1Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Md, USA.
JAMA
|March 5, 1998
まとめ
サブクリニック疾患や機能的制限は,高齢者の死亡率を有意に予測します. 病気の重症度,弱さ,障害の客観的な測定は,5年後の死亡リスクを予測するための重要な指標です.
科学分野:
- ゲロントロジーはゲロントロジーの学科です.
- エピデミオロジー エピデミオロジー
- 内科内科は,内科の内科である.
背景:
- 高齢者の死亡率は多因性である.
- 死亡リスクに対するサブクリニック疾患の独立した貢献は十分に理解されていません.
研究 の 目的:
- コミュニティに住む高齢者の死亡率を予測する疾患,機能,個人の特徴を特定する.
- 65歳以上の人々の死亡率の共同予測要因を決定する.
主な方法:
- 5年間のフォローアップを伴う将来的な人口ベースのコホート研究.
- 4.25年間のフォローアップでアフリカ系アメリカ人の検証コホート.
- 65歳以上の5201人 (オリジナル) と685人 (検証) の参加者の78の特徴を評価した.
主要な成果:
- 主なコホートでは5年以内に646人の死亡 (12%) が発生しました.
- 年齢,男性性別,低所得,喫煙,高血圧,高血糖,低アルバミン,肺機能障害,心臓病,認知/機能的欠陥を含む20の特徴によって独立して死亡率が予測されました.
- 客観的な疾患の測定は,閉塞性心不全を除いて,臨床歴よりも強力な予測指標でした.
結論:
- サブクリニカル疾患と疾患の重症度は,老人の5年間の死亡率を客観的に予測します.
- 男性性,貧困,身体不活性,喫煙,弱さ,障害も重要な予測要因である.
- 病気の定量的な測定は,死亡リスクの評価のための臨床歴と比較して優れた予測価値を提供します.
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