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Updated: Jun 27, 2026

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
14:23

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses

Published on: August 31, 2014

新種のCDK9関連C型サイクリンは,HIV-1 Tatと直接相互作用し,その高親和性,ループ特異的な結合をTAR RNAに媒介する

P Wei1, M E Garber, S M Fang

  • 1Regulatory Biology Laboratory, The Salk Institute for Biological Studies, La Jolla, California 92037-1099, USA.

Cell
|March 10, 1998
PubMed
まとめ

HIV-1 Tatタンパク質は,サイクリンTを使用して,TARRNAへの結合を強化し,転写を促進します. この相互作用はウイルスの遺伝子発現に不可欠であり,ネズミの細胞におけるヒトサイクリンTによって救出され得る.

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Tandem Affinity Purification of Protein Complexes from Eukaryotic Cells11:30

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