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Updated: Jul 16, 2026

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
10:28

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers

Published on: September 20, 2018

ポリコンブとトリソラックス群のタンパク質は,クロマチンの断熱器の機能を媒介する

T I Gerasimova1, V G Corces

  • 1Department of Biology, The Johns Hopkins University, Baltimore, Maryland 21218, USA.

Cell
|March 10, 1998
PubMed
まとめ

ジプシーのようなクロマチン隔離剤は,Su (Hw) とMod (mdg4) タンパク質によって調節され,ポリコンブ (PcG) とトリソラックス群 (TrxG) タンパク質と相互作用する. これらの相互作用は,より高次元の染色体領域を組織することによって,強化剤-促進剤のコミュニケーションに影響を与えます.

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Euchromatin

The extent of chromatin compaction can be studied by staining chromatin using specific DNA binding dyes. Under the microscope, the dense-compacted regions take up more dye, appearing darker, while the less-compact areas take up less dye and appear lighter. Based on the compaction level, chromatins are classified into two primary forms – euchromatin and heterochromatin.
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