ブラックタールヘロインに関連した創傷ボツリズムは,注射薬物中毒者の間で発生しています
D J Passaro1, S B Werner, J McGee
1Division of Communicable Disease Control, California Department of Health Services, Berkeley 94704, USA. dpass@ix.netcom.com
JAMA
|March 27, 1998
まとめ
ブラックタールヘロイン (BTH) の皮膚下または筋肉内注射は,創傷ボツリズム (WB) を発症させる主な危険因子です. この発見は,注射薬物使用者 (IDU) を治療する医療提供者にとって極めて重要です.
科学分野:
- 感染症 感染症は感染症です.
- 公衆衛生は公衆衛生である.
- 毒理学 毒理学 毒理学
背景:
- 創傷ボツリズム (WB) は,クロストリジウムボツリニウム神経毒によって引き起こされる重度の麻痺性疾患です.
- カリフォルニア州では",ブラックタール"ヘロイン (BTH) の使用に関連したWB症例が増加しています.
研究 の 目的:
- ドラッグを注射する人の間で,創傷ボツリズムの特定の危険因子を特定する.
- BTHの注射方法とWBの発達との関連を理解する.
主な方法:
- 症例対照研究が行われました.
- データは,26人のWB患者および110人の注射薬物使用者との対面面談および電話インタビューを通じて収集されました.
主要な成果:
- BTHの皮膚下または筋肉内注射は,WBと有意に関連していました (OR, 13.7).
- これらの経路で注射されたBTHとWBのリスクの間には,用量反応関係が観察されました.
- 皮膚や器具の清掃や針の共有などの慣行は,WBリスクに影響しませんでした.
結論:
- 創傷ボツリズムの主なリスク要因は,黒タールヘロインの皮膚下または筋肉内注射である.
- 医師は,特にBTHが蔓延している米国西部の医師は,注射薬物使用者のWBリスクを認識する必要があります.
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