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生存可能な心筋膜:疫学,検出,および臨床的影響
1Department of Cardiology, Cleveland Clinic Foundation, OH 44195, USA.
Lancet (London, England)
|March 31, 1998
まとめ
心筋梗塞 (MI) の生存者は心不全を発症する可能性がありますが,活力のある心筋は回復することができます. この組織を特定し,救出するためにMI治療法を再評価することで,患者の結果と予後を改善することができます.
科学分野:
- 心臓病学 心臓病学
- 再生医学は,再生医療である.
背景:
- 心筋梗塞 (MI) 治療は死亡率を低下させるが,生存者はしばしば心不全を発症する.
- 心臓発作後の心不全の現在の治療法は,有効性が限られている.
- 心臓移植は,最終段階の心不全の治療に限られた選択肢です.
研究 の 目的:
- 心筋梗塞の現在の治療アプローチを再評価する.
- M.I.後の生存可能な心筋の回復の病原性を調べる.
- 回復可能な心臓組織を特定するための技術を見直し,臨床的意味について議論する.
主な方法:
- 心筋梗塞の病原性と回復に関する文献レビュー.
- 活性の高い心筋膜を特定するための技術の分析.
- 救出可能な組織の臨床的影響の評価.
主要な成果:
- 心筋梗塞に罹患したセグメントの約40%は,自発的にまたは再血管化後に回復することがあります.
- 活性の高い心筋梗塞の持続性は,前述の不血性損傷の理解に異議を唱える.
- 心筋再血管化は,選択された患者の症状,運動能力,および予後を改善することができます.
結論:
- 生命力のある心筋梗塞後の心筋梗塞を特定し,救出することは極めて重要です.
- 生存可能な組織を持つ患者では,再血管化戦略を検討する必要があります.
- 回復可能な心筋膜に関するさらなる研究は,心不全の管理を最適化することができます.
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