ニューロピリン-1は,血管内皮成長因子のためのアイソフォーム特異的受容体として,内皮細胞および腫瘍細胞によって発現します

S Soker1, S Takashima, H Q Miao

  • 1Department of Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

Cell
|April 7, 1998
PubMed
まとめ

ニューロピリン-1は,第3の血管内皮成長因子 (VEGF) 受容体として作用し,特にVEGF165.5を結合します. この相互作用は,VEGF165がKDRと結合することを強化し,血管新生と内皮細胞の活動を調節します.

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