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Updated: May 5, 2026

Analysis of Physiologic E-Selectin-Mediated Leukocyte Rolling on Microvascular Endothelium
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カルモジュリンは,プロテアゼ依存メカニズムを通じて,L-セレクチン粘着分子の発現と機能を調節する.

J Kahn1, B Walcheck, G I Migaki

  • 1Boehringer Ingelheim Pharmaceuticals, Inc., Department of Immunological Diseases, Ridgefield, Connecticut 06877, USA.

Cell
|April 7, 1998
PubMed
まとめ

カルモジュリンは,細胞粘着分子であるL-セレクチンに直接結合します. カルモジュリンを阻害すると,タンパク質分解経由でL-セレクチン分泌を誘発し,細胞表面タンパク質の新たな調節機構を明らかにする.

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