高齢の入院患者の死亡率の予測における機能的測定値の重要性
S K Inouye1, P N Peduzzi, J T Robison
1Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06504, USA.
JAMA
|April 29, 1998
まとめ
機能的測定は,高齢の入院患者の死亡率を有意に予測し,既存のリスク評価ツールを改善します. 機能的状態を組み込むことは,90日および2年生存のための予後精度を高めます.
科学分野:
- ゲリアトリック・メディシン (老年医学)
- 臨床流行病学 臨床流行病学とは
- 医療サービス 研究 医療サービス
背景:
- 身体的および認知機能の測定は,高齢の患者にとって重要な予後指標です.
- 現在のリスク調整指数では,これらの重要な機能的指標が含まれていません.
- これは,病気の負担と病院での結果の正確な評価を制限しています.
研究 の 目的:
- 90日間の死亡率と2年後の死亡率に関する機能的測定値の予測価値を評価する.
- 疾病指数の標準負荷に対する機能的対策の寄与を評価する.
- これらの貢献を高齢の入院患者で検証するために.
主な方法:
- 高齢の入院患者 (70歳以上) を対象とした2つの前向きなコホート研究.
- 開発コホート (n=207) と検証コホート (n=318).
- 機能的軸は,日常生活の活動,ミニメンタルステート試験,および高齢者のうつ病スケールを使用して開発されました.
主要な成果:
- 機能的軸は,両方のコホートにおける死亡率を有意に予測した (P<.001).
- 機能的な測定は,5つの標準的な疾病負荷指標の予測能力を大幅に改善しました.
- "ダブルグラデント現象"が観察されました:死亡率は,疾患負担層内の機能的低下とともに増加しました.
結論:
- 機能的測定は,入院後の短期および長期の死亡率の強力な予測要因です.
- これらの措置は,既存の疾病負荷指標の予後能力を大幅に高めます.
- 高齢の入院患者の最適なリスク調整には,機能的状態の変数の統合が必要です.
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