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Updated: Aug 2, 2026

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Rap1は,神経成長因子によって誘発された持続的なMAPキナーゼ活性化を媒介する

R D York1, H Yao, T Dillon

  • 1The Vollum Institute for Advanced Biomedical Research, Oregon Health Sciences University, Portland 97201, USA.

Nature
|April 29, 1998
PubMed
まとめ

神経成長因子は,持続的なミトゲン活性化タンパク質 (MAP) キナーゼ活性化によって神経細胞の分化を引き起こす. この持続的な活性化は,初期のRas依存経路と異なる小さなGタンパク質Rap1に依存し,細胞の成長と分化を促進します.

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