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Updated: Aug 16, 2026

Transverse Aortic Constriction in Mice
08:25

Transverse Aortic Constriction in Mice

Published on: April 21, 2010

Gαq過剰発現したマウスの圧力過負荷高縮症の解消

Y Sakata1, B D Hoit, S B Liggett

  • 1University of Cincinnati and Cincinnati Veterans Administration Medical Center, Ohio 45267-0542, USA.

Circulation
|May 12, 1998
PubMed
まとめ

心臓細胞におけるGqシグナル伝達の過剰発現は,胎児の遺伝子発現と収縮性の低下を引き起こす. これは,圧力の過剰負荷下での不適応性高縮および心不全につながり,心臓の適応に関する現在の理解に挑戦します.

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