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Updated: Aug 15, 2026

Biochemical Reconstitution of Steroid Receptor•Hsp90 Protein Complexes and Reactivation of Ligand Binding
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グルココルチコイド受容体によるクロマチンの改造には,BRG1複合体が必要です

C J Fryer1, T K Archer

  • 1Department of Obstetrics & Gynaecology, University of Western Ontario, London Regional Cancer Centre, Canada.

Nature
|May 20, 1998
PubMed
まとめ

プロゲステロン受容体は,hBRG1/BAF複合体とのグルココルチコイド受容体相互作用を阻害することによって,クロマチンからの遺伝子活性化を抑制する. これは,受容体活性化とクロマチンの改造機能を分離することが可能であることを示唆しています.

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