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Updated: Jun 20, 2026

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
11:42

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

DNAに結合したチロシン酸化STAT-1ジメルの結晶構造

X Chen1, U Vinkemeier, Y Zhao

  • 1The Rockefeller University, New York, New York 10021, USA.

Cell
|June 18, 1998
PubMed
まとめ

シグナルトランスデューサーとトランスクリプションアクティベーター1 (STAT-1) のホモディマー結晶構造は,DNAの周りにC形のクランプを明らかにします. 特定のSH2ドメインの相互作用はDNA結合を安定させ,遺伝子調節における役割を示唆している.

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Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis10:22

Protein Purification-free Method of Binding Affinity Determination by Microscale Thermophoresis

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PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase09:31

PCR Mutagenesis, Cloning, Expression, Fast Protein Purification Protocols and Crystallization of the Wild Type and Mutant Forms of Tryptophan Synthase

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