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Updated: Aug 2, 2026

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay
09:07

Detecting the Ligand-binding Domain Dimerization Activity of Estrogen Receptor Alpha Using the Mammalian Two-Hybrid Assay

Published on: December 19, 2018

エストロゲンはAT1受容体の遺伝子発現をin vitroおよびin vivoで調節する

G Nickenig1, A T Bäumer, C Grohè

  • 1Klinik III für Innere Medizin, Universität zu Köln, Germany. georg.nickenig@uni-koeln.de

Circulation
|June 19, 1998
PubMed
まとめ

エストロゲン欠乏はAT1受容体の発現を増加させ,高血圧と動脈硬化に寄与する. エストロゲン置換療法は,この効果を逆転させ,心臓血管の健康に対する保護的役割を強調します.

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