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Updated: Jun 16, 2026

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics
06:00

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics

Published on: May 14, 2016

DNA複製の阻害体であるジェミニンは,ミトーシス中に分解される

T J McGarry1, M W Kirschner

  • 1Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Cell
|July 11, 1998
PubMed
まとめ

新しいタンパク質であるジェミニンは,RC前へのMCM複合体の組み込みをブロックすることによって,DNA複製を阻害します. メタフェーズからアナフェーズへの移行時の双子の破壊は,次の細胞サイクルでDNAの複製を可能にします.

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Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors06:07

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