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Updated: Aug 8, 2026

Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery
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Development of Cell-type specific anti-HIV gp120 aptamers for siRNA delivery

Published on: June 23, 2011

HIV gp120エンベロップグリコタンパク質の構造は,CD4受容体とヒトの中和抗体との複合体である

P D Kwong1, R Wyatt, J Robinson

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA.

Nature
|June 26, 1998
PubMed
まとめ

ヒト免疫不全ウイルス (HIV) が細胞に侵入することを理解することは極めて重要です. この研究は,HIV gp120がCD4に結合し,抗体を中和する構造的基礎を明らかにし,ウイルスの免疫回避に関する洞察を提供している.

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