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Updated: May 5, 2026

Molecular Analysis of Endothelial-mesenchymal Transition Induced by Transforming Growth Factor-β Signaling
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トロンボスポンジン-1は,TGF-β1の主要な活性化剤であり,生体内では

S E Crawford1, V Stellmach, J E Murphy-Ullrich

  • 1Robert H. Lurie Cancer Center, Department of Pathology, Northwestern University Medical School, Chicago, Illinois 60611, USA.

Cell
|July 10, 1998
PubMed
まとめ

トロンボスポンディン-1 (TSP-1) は,生体内で変形成長因子-β1 (TGF-β1) を有意に活性化する. TSP-1ペプチド治療は,TGF-β1欠乏による肺および臓の異常をマウスで逆転させました.

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