心停止の発生における日々の変動:初期および再発エピソード
M Peckova1, C E Fahrenbruch, L A Cobb
1Department of Biostatistics, University of Washington, Seattle 98105-4689, USA.
Circulation
|July 17, 1998
まとめ
心停止は毎日のパターンを示し,朝と夕方にピークに達し,日常活動に関連しています. 再発性心停止は,女性を除いて,時間関連性を示さなかった.
科学分野:
- 心臓病学 心臓病学
- クロノバイオロジー クロノバイオロジー
- 公衆衛生は公衆衛生である.
背景:
- 心停止の発症の時間的パターンを理解することは,急性心血管疾患のメカニズムを解明するために重要です.
- 以前の研究では,心臓発作の発生率が昼間と季節によって変化し,朝と夕方にはピークに達することが示されていました.
- 昼間の時間と再発性心停止の関係については,まだ調査されていない.
研究 の 目的:
- 病院外での心停止の時間的変動を調査する.
- 昼間の時間と再発性心停止の関連性を調べる.
主な方法:
- シアトル消防署が参加した6603人の病院外心停止の分析.
- 時間のパターンの検討,昼間の変動と再発性停止のタイミングを含む.
- 心拍数と生存率に調整した統計分析.
主要な成果:
- 心停止は,2つのピーク (8-11 AMと4-7 PM) と夜間発生率の低い昼間変動を示した.
- 夕方のピークは主に心房細動と関連していたが,朝のピークは他のリズムを示した.
- 心停止と生存率は,より顕著な昼間の変動を示した; 女性の場合を除いて,再発性停止の全体的な時間関連は見つかりませんでした.
結論:
- 心臓発作は予測可能な日々のパターンをたどり,日々の活動に影響される可能性が高い.
- この発見は,疾患の特徴だけではなく,外部の活動が心臓発作を誘発する可能性があるという仮説を裏付けている.
- 繰り返しの逮捕における関連性の欠如は,活動によって引き起こされたイベントを示唆し,女性の特定のパターンが観察されています.
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