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Updated: Aug 5, 2026

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag
08:55

Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag

Published on: December 14, 2017

二次性14-3-3タンパク質は,Rafキナーゼ活性のための重要なコファクターです

G Tzivion1, Z Luo, J Avruch

  • 1Department of Molecular Biology, Massachusetts General Hospital, Harvard Medical School, Boston 02114, USA.

Nature
|July 17, 1998
PubMed
まとめ

14-3-3タンパク質は,ラフキナーゼの活性に不可欠であり,その不活性状態を維持し,その活性構造を安定させます. ディメリック14-3-3は,Rafの活性化とMAPキナーゼ経路における機能に不可欠である.

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Bioluminescence Resonance Energy Transfer (BRET)-Based Assay for Measuring Interactions of CRAF with 14-3-3 Proteins in Live Cells

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