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Updated: May 11, 2026

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells
10:27

Spatio-Temporal Manipulation of Small GTPase Activity at Subcellular Level and on Timescale of Seconds in Living Cells

Published on: March 9, 2012

新型ATM関連タンパク質TRRAPは,c-MycおよびE2Fオンコプロテインの重要なコファクターである

S B McMahon1, H A Van Buskirk, K A Dugan

  • 1Department of Molecular Biology, Princeton University, New Jersey 08544-1014, USA.

Cell
|August 26, 1998
PubMed
まとめ

研究者は,c-MycとE2F-1と相互作用するタンパク質であるTRRAPを特定しました. TRRAP機能をブロックすると,腫瘍性変異が抑制され,これらの経路におけるコファクターとしての重要な役割が示唆されます.

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Intracellular Phosphoflow Cytometry of Acute Myeloid Leukemia Patient-Derived Xenotransplants07:38

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