アトピー性湿疹と家庭用水の硬さについて
N J McNally1, H C Williams, D R Phillips
1Health Research Group, Department of Geography, University of Nottingham, University Park, UK.
Lancet (London, England)
|August 26, 1998
まとめ
硬水への曝露は,幼児におけるアトピー性湿疹のリスクを増やす可能性があります. この研究では,小学校の生徒の水の硬さと湿疹の流行の間の直接的な関連性が見つかりました.
科学分野:
- 環境衛生 環境衛生 環境衛生
- 皮膚科 皮膚科について
- エピデミオロジー エピデミオロジー
背景:
- アトピー性湿疹 (湿疹) に寄与する環境要因は完全に理解されていません.
- 家庭用水の硬さは,湿疹の発症の潜在的な危険因子です.
- この生態学的研究は,学校の子供における水の硬さと湿疹の流行の関連性を調査しています.
研究 の 目的:
- 家庭用水の硬さとアトピー性湿疹の流行の関係を調べる.
- ノッティンガムシャー州の小学校と中学校でこの関係を評価するために.
主な方法:
- 4141人の小学生と3499人の中学生からのアンケートデータを利用した生態学的研究設計.
- 地理情報システム (GIS) は,エクゼマの発生率データを,家庭用水の硬さカテゴリーにリンクした.
- 性別,年齢,社会経済的な地位,医療へのアクセスなど,潜在的な混同因子に関する統計的調整が行われました.
主要な成果:
- 水の硬さと小学生の1年期および生涯エクゼマの罹患率との間に有意な直接的な関係が観察されました.
- 水の硬度が最も高いカテゴリーと最も低いカテゴリーの1年間の流行に対する調整されたオッズ比率は,小学生の1.54 (p<0.001) でした.
- 水の硬さに関連した中等学校の集団では,湿疹の有意な傾向は見られませんでした.
結論:
- 硬い家用水への曝露は,小学校に通う年齢の小児で湿疹を発症するリスクを高める可能性があります.
- この関連性を確認し,根本的なメカニズムを探求するために,さらなる研究が必要である.
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