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Updated: Aug 9, 2026

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry
11:37

Analyzing Protein Dynamics Using Hydrogen Exchange Mass Spectrometry

Published on: November 29, 2013

HSF90 (HSP90複合体) によって熱ショック転写因子HSF1の活性化を抑制し,HSF1とストレス感受複合体を形成します

J Zou1, Y Guo, T Guettouche

  • 1Department of Biochemistry and Molecular Biology, University of Miami School of Medicine, Florida 33101, USA.

Cell
|September 4, 1998
PubMed
まとめ

熱ショックタンパク質90 (Hsp90) は,熱ショック転写因子1 (HSF1) の主要な抑制剤として作用する. Hsp90レベルを低下させると,HSF1が活性化され,熱ショック遺伝子発現の調節における重要な役割が明らかになる.

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