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Updated: Aug 18, 2026

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs
10:37

Toeprinting Analysis of Translation Initiation Complex Formation on Mammalian mRNAs

Published on: May 10, 2018

ユカリオトのリボソームは,イニシアーションコドンを見つけ出すために,イニシアーション因子1と1Aを必要とします

T V Pestova1, S I Borukhov, C U Hellen

  • 1Department of Microbiology and Immunology, State University of New York Health Science Center at Brooklyn, 11203, USA. tpestova@netmail.hscbklyn.edu

Nature
|September 11, 1998
PubMed
まとめ

2つの重要な翻訳開始因子,eIF1とeIF1Aは,真核リボソームがメッセンジャーRNAのスタートコドンを発見するために不可欠です. その欠如は,適切な複合体の組み立てを妨げ,タンパク質合成の開始を妨げます.

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